Authentic Boredom is one of the first to come out with the “big in ‘06″ predictions for the web. He does a pretty good job of it too.
The quick skinny:

• Page refreshing - out
• Fisher Price look - out
• Lucidia - staying
• Drop shadow, gradient and dotted line - staying
• Rounded corners - staying
• Tags - In
• Helvetica with negative letter spacing - in
• The grid - in
• Mobile - in
• Fluid Layouts - in
• Javascript & DOM scripting - in

Read the article for his wild card. Bold predictions for the savvy designer, 2006 edition ~ Authentic Boredom